Please help me review the schematic of TMUX1574
Is it possible to select only SXA-DX for TMUX1574DYYR, and pull down the SEL pin 10k to ground?
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Yes, you can pull down SEL to select only the SxA-Dx connection. If a strong pulldown is not needed, the TMUX1574 has an internal 6Mohm pulldown that can save on components.
If this is a high frequency application, grounding the SxB pins is suggested since they can pick up noise when floating.