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TMUX1208: pin connection

Part Number: TMUX1208

Hi team,

I want to confirm 2 questions.

1. The VSS pin of TMUX1208 corresponding to 1108 is NC. If that pin is connected to GND, will it have any bad effect?
2. Can the EN pin and A0~A3pin be directly connected to Power or GND? Or must there be pull up and down resistors?

Thanks a lot!

Best regards,