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PMP20183: how to make the output HV is tunnable?&How to Inverting the Boost HV to -200V?

Part Number: PMP20183

1. How to make the output HV is tunnable with the control of MCU(PWM for wxample)? The HV range is 50-200V, is tunable.

2 How to Inverting the Boost HV to -200V? I need a negtive HV output.

Thanks.