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PMP9282: PMP9282 on the reference design Optocoupler pin not connect to any flag

Part Number: PMP9282

I have three questions.

1. On the reference design Optocoupler (U2) (Optp_E_GND) not connected to any flag (Picture attached) and 1N4148W-7-F (Vout) not connected. 

2. Should I solder the DNP components?. Could please explain why DNP components are shown in the reference design. 

3. Any alternative for PA3855.005NL? Because currently no manufacture.

Ref Link:https://www.ti.com/tool/PMP9282

Thank You,