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CC2640R2F: HAL_ASSERT_CAUSE_HARDWARE_ERROR

Part Number: CC2640R2F

My application, based on the simple peripheral project using SDK 2.40.0.32 is encountering an assert with the assertCause of HAL_ASSERT_CAUSE_HARDWARE_ERROR.  I would appreciate any help in understanding exactly what this error might be, if it is truly a hardware fault or some other condition.