CC2530-CC2592EM-RD: ZBufferFull how can i clear it?

Do you send ZNP command very fast? Can you elaborate what you do to see this ZBufferFull issue?

No so fast.
My problem very close like the attachment link. We have net this net consist 5 ZED and 3 ZR and ZC. All ZED join to same ZR (Don't have direct join to ZC ) ZC is point of collect my data(all devices send data to ZC. APS Ack is enable )
If ZC is switch of on few minutes (about 20 and more) all ZED lost coordinator and coordinator dosen't get messages from ZED. If I try to send messages to ZED from ZC (or other device) I get ZNwkNoRoute status(0xCD) in AF_DATA_CONFIRM. If i try send messege to other device (ZR or ZC) all ok.
After reboot ZED they normal to join to net. And work without any problem..

So, is your problem anything to do with ZBufferFull? Or it is ZNwkNoRoute status(0xCD) issue?

I get both. At weekend I will try to make extended experement.. And get more data.

Those are two different issues. Please test again and post your test steps so I could try to help.