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ADS1298R: Lead Derivations usage in actual firmware

Part Number: ADS1298R
Other Parts Discussed in Thread: ADS1298

as per the user guide of ADS1298R evaluation module, these are the formula used for lead voltage values from the actual 10 leads. 

I am converting the binary values i am getting from the SPI into actual microvolts. Should I then use these voltages of individual channels and put in this above formula to get the leads voltages or ADS1298 

is doing it automatically and I just have to convert binary values to analog voltages?