TSC2004: Read and write to TSC2004 Configuration register.

I am using TSC2004 controller in my project. I have to write and read from configuration register. As per the datasheet, I have to send slave address [0x48] followed by register address. During sending register address, do I want to set the 0th bit of Control Byte 0 to indicate Read operation from the register or Setting the Read bit while sending the slave address is enough?