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ADS124S08: How many RTD can be handled by 1 ADC

Part Number: ADS124S08

Tool/software:

Hi exparts,

In this application note, maximam 4 RTD are connected to ADC. How many RTD can be handled by 1 ADC without MUX like previous E2E thread?

Can a single ADC handle 24 RTDs with MUX? If so, what are the disadvantages of using MUX?

Regards,

Hiromu