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ADS1220 Vref value for bipolar input measurement

Other Parts Discussed in Thread: ADS1220

Hi,

I would like to use ADS1220 in one of my single ended bipolar voltage measurement application which ranges from +2v to -2V.

Can i use the internal Vref of 2.048V to measure the above input?

AVDD and AVSS are +2.5V and -2.5V respectively,

DVDD is 3.3V