We have noticed the gain drift on the ADS1278 to be as high as 1000 ppm/c. For instance, converting a DC voltage on a channel while the temperature is increasing shows a notch like response in the converted value versus temperature. To verify it is not the input signal, we also captured the differential input to the ADC with a DMM while sweeping in temperature. A plot of the converted value vs temperature shows a notch at around 1000 ppm/c at a specific temperature. Once the notch is passed by continuing to drive temperature up, the ADS1278 works fine. In fact, it works fine for most of the temperature range, there is a very specific temperature for which the gain seems to drift excessively. We see this on other channels as well but at different specific temperatures. We have successfully used the ADS1278 in other designs. My question is, what kinds of things can contribute to such excessive gain drift in the ADC that occur at very narrow temperature ranges while the greater ADC temperature performance is inline with 1.2 ppm/c?