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ADS8688 Measuring with floating ground

Other Parts Discussed in Thread: ADS8688

Hello everyone,

                       I have another query about ads8688. We want to measure the signal with floating ground (i.e with respect to IC ground), without connecting negative terminal to the IC ground in order to protect the circuit from reverse polarity. Is this possible without using any external reverse polarity protection circuits?

Regards,

Varaprasad.