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ads1291 sample data found many glitch. help!

Other Parts Discussed in Thread: ADS1291, ADS1246

hi, I'm a newbie on using deltasigma adc. I am  making a  ppg  device( something like pulse oxymeter, but have more ppg related function) with ads1291.  

light signal sampled with a I-V amplifier, then feed to the adc input.

however I found  many glitch like the following, it ruined my data. :

I've tried  many methods like add a buffer or a Cext next to  the adc input pin. However it doesn't work.

this is my schematic:

the setting is:

PGA:  6

datarate: 500

though it seems these glitch can be filtered, but I feel it should be a simple error i made and can be fixed.

for i found the same glitch on ads1246. 

Thanks for help