The data sheet lists:
"Case 1: LED forward voltage is such that a voltage of 3.3 V (for example) is acceptable on LED_DRV_SUP. In that case, a single 3.3-V supply can be used to drive all four pins (RX_ANA_SUP, RX_DIG_SUP, TX_CTRL_SUP, LED_DRV_SUP). Care must be taken to provide some isolation between the transmit and receive supplies because the LED_DRV_SUP carries the high switching current from the LEDs."
To me it reads that all four pins can be supplied by a single 3.3V supply but then says TX and RX supplies must be isolated. So can a single supply be used to power both?