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DS92LX1621: DOUT+ - differential pair tarce impedance

Part Number: DS92LX1621
Other Parts Discussed in Thread: DS92LX1622

Hi,

   on data sheet, 100 ohm differential impedance, does it request differential pair trace impednace of  OUT+/- pins control at 100ohm on layout? 

if the chip is put near connector, and external cable to DS92LX1622, which impedance should I control to 100 ohm? cable or total (trace layout on PCB + connector + cable+...)?