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Linux/ISO3082: Can I use RTS signal of STM32 USART to Control the ISO3082 DE pin ?

Part Number: ISO3082

Tool/software: Linux

In my design, Using STM32F103 + ISO3082 to implement the RS485 Communication.
The USART1_RTS is connected to DE Pin of ISO3082. And sometimes the Error ocurred.
I guess the DE timing is wrong.
How to Control the DE ? Using GPIO or RTS? Which is preferred ?
I think RTS is specially used for flow control ,but now Error ocurred.
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