TMS320F280049: Debugging two ISR code

I have my code implementing two ISRs with ISR nesting implemented virtually identical to TI example code, interrupt_ex3_sw_prioritization.c.   It all works as expected. My problem is with setting a breakpoint and debugging under CCS.  If I set a breakpoint in the code executing in the thread of the lesser priority ISR, I can single step through the code as expected but when I click the Run button, my program crashes in the weeds. Is there anything to be done to avoid the program crashing? To be sure you understand, my program does not crash if allowed to run without breakpoints.