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TMS320F28P550SJ: The execution time of the interrupt service routine is much longer when connected to the MCU in CCS

Part Number: TMS320F28P550SJ
Other Parts Discussed in Thread: UNIFLASH

Tool/software:

I am using the 28P550 controlCARD to develop a program. At the beginning of the interrupt service routine, I set the GPIO, and before exiting the interrupt, I clear the GPIO. I use this method to measure the interrupt execution time. However, I found that there is a significant difference in the interrupt execution time between directly programming the MCU and connecting to the MCU via CCS to execute the program. The execution time of the interrupt service routine is much longer when connected to the MCU in CCS, nearly ten times longer. What could be the reason for this?