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LM5170: Input GND and output GND are different

Part Number: LM5170
Other Parts Discussed in Thread: PMP21867,

Hi Team,

Customer want to use LM5170 to achieve -48V input & 12V output. I think LM5170 can be used without problem and have verified by PMP21867.

But in customer system, the input GND and output GND are different, which in reference design is same. So will two different GND have problem? Or must use a same GND? Thanks.

BRs,

Francis