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LM5160A: ISOGND & GND Capacitor

Part Number: LM5160A

In the isolated Fly-Buck application of the LM5160A, the example schematic from TI's datasheet (page 26) shows C3 as a 2200pF, 2000V capacitor between the ISOGND and GND.

What is the function of capacitor C3 and does it have a bearing on the VOUT ripple? Thanks.