Hi,
My TPS53355 would not start up and I checked VREG, it's at 0 V. The input is 12V, output is 1V. Following is my schematic:

Please help me!
Donald WU
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Hello Donald,
What is the load that is being applied? What is the EN voltage? Have you tried replacing the IC with a fresh one? It could have been damaged accidentally.
I would recommend following the Application Design in the datasheet as your conditions are fairly similar. You can also input your design in the excel design tool to ensure your design is stable. I attached the links below.
Excel Design Tool: https://www.ti.com/tool/download/SLURAZ7
Let me know if this helps.
Thanks,
Calan