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LM3466: Can this be used with a non-ground referenced constand current source?

Part Number: LM3466
Other Parts Discussed in Thread: LM3409

Tool/software:

We are using an LT3475 constant current driver which does not directly connect the LED anode to ground for PWM control.  Can I connect this "return" path to the LM3466 and still have it provide current balancing for multiple LED strings?