Tool/software:
I want to polarity voltage generation with common GND as picture.
That is -12V input to +5V output.
Is it no problem?

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Tool/software:
I want to polarity voltage generation with common GND as picture.
That is -12V input to +5V output.
Is it no problem?

I've not tried this configuration but the concern is that on the output side the GND is the LOW reference for +5V but on the input side the same GND is the HIGH reference for -12V. It might be ok to try this, if the input GND and output GND were isolated.
Steve