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LM74502H-Q1: Seeking Guidance on Protection ICs for 48V ECU Design

Part Number: LM74502H-Q1
Other Parts Discussed in Thread: LM74703-Q1, INA230, INA300, LM5148-Q1, LM74910H-Q1, LM74900Q1EVM

Tool/software:

Hi,

I’m designing an ECU PCB that will operate from a 48 V vehicle supply and must include input protection for reverse polarity, overvoltage, under voltage, overcurrent and ESD. After a few hours of preliminary research I’ve identified a short list of TI parts that seem to match the requirements, but I’d appreciate guidance on three points:

1) Are there better or more cost-effective alternatives (availability/stock matters) to the parts listed below?
2) What is the recommended sequence of protection devices from the input connector through to the buck converter?
3) Are there better combinations of ICs (or any missing device types) you would recommend for a 48 V automotive ECU input stage?
Parts I’ve shortlisted are:
1. Reverse-polarity / overvoltage: LM74502H-Q1, LM74703-Q1
2. Overcurrent / current-sense: INA300, INA230
3. Buck converter: LM5148-Q1
The Buck Convertor is responsible to for the conversion of 48V to 12V and 3.3V @8A each.