On page 8 of the LM2621 datasheet it suggests bootstrapping when the output is between 2.5V and 5.0V by connecting Vdd to Vout. In each of the application examples this is done through a 500Ω resistor (R1). What are the criteria for selecting a value for R1? On the bench (4V in, 5V out, 200mA) the 500Ω resistor produces >200mV of output ripple, and shorting it reduces ripple to acceptable levels.