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constant Current Supply 15A max 50V max

Dear All,

I am required to design a Constant Current Supply that would supply a  pre set current through a load. It is required the pre set current is also changeable. 

I can provide any DC input from 250V down to any. I intend to design my DC supply later.

Is there a TI IC I can use to this task of pushing in a constant currrent through a load? 

If there is a circuit diagram, or an example diagram could someone please share with me? it would help me a lot.