We have been having some troubles with the TPS22810, so I went back to the datasheet to search for more information on what might be wrong. I realized that while we assumed the thermal pad on the WSON package was connected to GND, there is nothing in the datasheet which actually specifies that. The only mention of the thermal pad is in the package drawing, which has no information on the electrical connectivity.
Can someone confirm or refute that the thermal pad should be connected to the part's GND? I would also advise a datasheet update so that this information can be found in the appropriate place in the future.