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Compiler/UCD3138: UCD3138 is only applied to Isolated Power ?

Part Number: UCD3138

Tool/software: TI C/C++ Compiler

Hello,  I was recently learning the UCD3138 chip, and met a question.

I noted "UCD3138 :Highly Integrated Digital Controller for Isolated Power" in datasheet, whether it can be used in non-isolated DC-DC converters, like Buck converter?

Looking forward to your reply,  thank you very much!