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LP5569: LP5569 Setting

Part Number: LP5569

Hi Team

please kindly help me with the question below:

1.Pin 5 EN/PWM: If LED is design with I2C control,could this pin Pull High?

2.Pin 6 CLK: under I2C Control mode, Pull High or Low?

3.Pin 7 GPIO/TRIG/INT:Keep floating?

4.Pin 22 VOUT: What is the function for this pin? How do I handle if this is not used?