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TPS92691: Separate power, boost MOSFET gate driver

Part Number: TPS92691

Hi. I have 2 questions.

We plan to use TPS92691 in boost topology. Vin 20-50V, Vout 54-58V. Iout 5A.

To minimize loses:

1. Can I use separate 12V for Vin and 48V for boost converter.

2. Can I use a MOSFET gate driver?

If anything will not work, please explain why.

Thank you,
Roman