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LM5122: Cascaded boost topology application

Part Number: LM5122
Other Parts Discussed in Thread: TPS40211-Q1,

Hi Team,

I would like to make a design of cascaded boost converter like image showing as below. I have no idea that the topology whether is appropriate for business point.

Spec may be

1. 12V to 48V(EV) ; 2. 80V to 380V(grid-connected)

I know we have corresponding boost converter could meet the spec, but I think cascaded topology may have some advantage like small filter size and efficiency(lower switching frequency).

Could you suggest me the appropriate solution to achieve boost converter in business and technical side(cost/size)?

One more question could I use the one controller to achieve cascaded topology if both duty cycle of switch is same?  

Roy