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TPS7B4254-Q1: About NC pin

Part Number: TPS7B4254-Q1

Hi TI-team

My customer have question.

Pin 2, 7 are NC. 

In EVM, it is connected to GND.

Can these be used without being connected (OPEN)?

What is the problem if it is not connected to GND?

Best Regards,

Koji Hayashi