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Kazuto-san,
Unfortunately TPS2121 cannot support USB OTG due to the reverse current protection feature, it would not be able to provide sufficient current before blocking the reverse charging.
A possible alternative is to mux the power to the host with 2 diescrete load switches which have sufficient reverse current current capability for OTG, or add an antiparallel load switch so that it is function as forward conduction when USB OTG is desired.
I hope this helped answer your question, if you have any other questions on this please let me know.
Best
Dimitri