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Regulators

Other Parts Discussed in Thread: TPS63036, TPS55288
in the product we are developing, which uses a Lithion battery single cell (2.8v to 4/35V) as power source, we are using two regulators:
- TPS630250RNCT for 3.3V regulator, load is about 3Amp
-  TPS61230ARNST for 5.5V output, load is about 1-2Amp. The max input is 4.5V, is this a concern for the battery cell input ?
 
Because we also charge the battery in the device in a charger, we are seeing some voltage spike transient when plugging the device into a charger. The ambient temperature in the enclosure is -5 to 85C.  
 
Wanted to know:
- The voltage spikes/transient: if this can potential damage the device ? 
- With the temperature as I described above, will this be any concern for the TI regulators operation ?