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BQ40Z50-R2: Smoothing

Part Number: BQ40Z50-R2

Do you have to do the chemID characterization with the proper function of smooth enabled or disabled?  In other words, if smoothing  is disabled and battery characterized for a custom chemID - then would the characterization need to be redone if smoothing is intended to be enabled (or vice versa).

Please advise if the status of the smoothing feature is independent of chemID characterization?