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Question about TPS5450-EP

Other Parts Discussed in Thread: TPS5450

In my application, the ground side of R2 in the resistor divider will be connected to an output of DAC since I want to adjust the output voltage of TPS5450 by this way.

My questions are:

1.      Is the reference voltage 1.2221V of TPS5450 fixed?

2.      For example, if the ground side of R2 is set to 1V, the tap at Vsense only detects 0.96V; does this mean the output voltage will be much higher than if the ground side of R2 is set to 0V?

3.      How to precisely calculate the output voltage by this configuration?

Thanks.