I am currently planning on using the TMP112 on 3.3V in a dual supply (2.2V and 3.3V) application (a thermostat, to be precise). This, however, requires a PCA9306 to translate the I2C bus levels. I noted the formula in the TMP112 datasheet for computing the error caused by using the TMP112 on non 3.3V supplies, however, if the device is calibrated at 2.2V and 25degC, will that "calibrate out" the readout error caused by running the sensor at 2.2V? Also: what effects would the SOT563's rather high Theta-JA of 260+K/W have on temperature sensor accuracy and response? Would it simply cause the sensor to be slower to react to changes in temperature? (I'm using it to read the ambient air temperature here, of course :).