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Hello Steve,
The effects of noise and stray capacitance can be reduced by using shielded cables with the shields connected to GND, but as a rule we don't recommend running I2C signals over lengths greater than 1m. I agree with Jayant's suggestion to read the I2C data with a micro and convert to a more robust protocol that's intended for greater transmission distances.
Best regards,
Ian Williams
Linear Applications Engineer
High Performance Linear