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AFE4410: Can I shut down RX_SUP and TX_SUP while keeping IO_SUP ON?

Part Number: AFE4410
Just to save a little bit of power, I am thinking to shut-down, from time to time, RX_SUP and TX_SUP while keeping the IO_SUP and I am wondering if this is possible.
On page 5 of the AFE4410 datasheet I have found that IO_SUP should be =< RX_SUP and RX_SUP should be =< than TX_SUP.
Does it mean that I am not allowed to shut-down RX_SUP and TX_SUP while keeping IO_SUP ON?
Thanks,
Cezar