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AFE4490: stops working for some time

Part Number: AFE4490

Hello there. 

So i am building a SPO2 device. I am using the AFE4490 and everything is working fine.
Just after some time the SPI-connection interrupts for some seconds and than works again for some time. 
As far as i measured the ADC_RDY spike disappears for this time, so i guess this is the problem.
The power supply works fine.

Did you deal with problems like that ?