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CCS v5 with Matlab R2010b

I'm using CCS Version: 5.1.0.07001 with Matlab R2010b to program DSK C6416. I have configured the target board iin CCS. However, when I type ccsboardinfo into Matlab command window, it always announce error:

??? Cannot start CCS application (COM error code: 0x80070002). Verify that
your CCS software is installed and configured properly.

Error in ==> ccsboardinfo at 68
            ccssetup.Connect(); % Connect to CCS Setup

Does CCS (v5) which comes with standard Eclipse  be able to support Matlab?