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Target must be connected before loading program

OS: Windows 7 SP1, 64-bit

CCS: 6.1.3.00033

Device/Board: 2x SmartRF06 with CC2650EM-7ID, XDS100v3

Issue:

After using the above system and components without issue for a number of months, I am no longer able to load any new code onto either of my CC2650EM's via the SmartRF boards.  I don't recall making any changes to the system so I am at a loss as to what to try next.  When I try to debug, I get the following two messages in the Console:

Cortex_M3_0: GEL Output: Memory Map Initialization Complete.
Texas Instruments XDS100v3 USB Debug Probe_0/Cortex_M3_0 : Target must be connected before loading program.

I've perused the forums here a bit and did not find anything obvious that would help.

Thanks,

Adam