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CC2640R2F: programming in 4x4 cc2640r2f using CCS

Part Number: CC2640R2F

I have referred to a simple link custom board link but I didn't understand much that what is necessary changes to debugging 4x4 cc2640r2f so I posted a query. I have a custom board that has 4x4 cc2640r2f MCU. I need to know what is the required changes.