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CC2541: peripheral losing connection if using I2C (BLE-CC254x-1.4.0)

Part Number: CC2541

cc2541 based peripheral Loosing connection to a Central, if send some data (every second) using I2C (updating an OLED display).

I2C is not currently using IRQ or DMA.

Is there a parameter that  will  allow more time to user code before dropping connection ?

Will IRQ based I2C communication will prevent dropping connection ?

Other options ?