Part Number: CC2652R
Other Parts Discussed in Thread: SYSCONFIG,
Hello,
I went through the DIO chapter.According to this screenshot, from this TRM page, can you confirm if I could use any of the available DIOs for I2C interfaces?

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Hello Ryan,
You can use any available DIO for I2C on the CC2652R. It can be configured using SysConfig and the I2C TI Driver so that you will not need to handle the registers directly.
Regards,
Ryan