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Can I use 2 lines UART in PTM mode?

Other Parts Discussed in Thread: CC2541

I am working on PTM mode on CC2541 keyfob application. To support PTM, I need to save pins for UART interface.

When flow control is enabled, UART needs 4 lines.

I wonder for PTM mode, can I disable UART flow control, so that I can save 2 pins for UART interface?

Is there any requirement regarding to UART flow control in PTM mode? 

Regards,

Jack