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Custom designed PCB runs with debugger but not with CR2032 Cell

Other Parts Discussed in Thread: CC2541

Hello all of you
i have designed a custom PCB with cc2541 its working very good with the debugger attached every BLE operations works.
now that i want to run it with the CR 2032 Cell it does not even turn ON. as if it is dead :)
my design is  very close to key fob i have two buttons one of them i use to turn the PCb on but it is not working with the cell

See my previous post for schematics and PCb board image.


Any suggestions will be greatly helpful
thanks