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CC2640 RF performance on a two layer board

Other Parts Discussed in Thread: CC2640

In my application I am planning on using the CC2640 mounted on a two layer board. Will there be any negative impact on the the RF performance because of the two layer board? We are planning to use this two layer board to mount the chip as well as a PCB antennae or chip antennae. I have not seen anything in the datasheet or design guide regarding this and I would like to make sure.