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Sending data via I2C from 22650

I am using a 2650 EM from the evaluation kit (that came with the SmartRF06 EB). I am trying to create a system where the 2650 is a transmitter, and another PIC16 microcontroller that I have (PIC16F1503) is the receiver. I want to know that when using I2C to send data, in form is the data received? Can I just send an 8-bit word, or does it have a lot of headers etc. accompanying it?

The application is lighting control. I'm trying to make this system as simple as possible.  I think I2C requires at least an address in the header, but I'm not sure. So I guess it all goes right to the receiver. And the receiver will know its own address. But I wonder how to customize this for each bulb? And how to tell the transmitter which addresses are used, and which are mounted where...it seems like a LOT of software development. Am I right in these assumptions so far?

Going off of this, how many addresses can Bluetooth pair with, from an industrial standpoint? I read somewhere that there is no limit to the number of pairings possible, except for any limitations made by the platform or Bluetooth software stack. How big is the stack/ how much does it allow? I just want to transmit an 8-bit word...

Any thoughts?