The CC2540 reference designs use an Epson Toyocom MC-306 32.768 kHz crystal in a 4-SOJ (5.50mm pitch) package that is 8.00mm x 3.20mm (x 2.38mm high). Other than price and having the room to spare, was there a reason not to use the similar but smaller 2-SMD crystals that are 3.20mm x 1.50mm (x 0.8mm to 0.9mm high) such as the AVX ST3215SB32768H5HPWAA (to name but one)? Are there any concerns with assembly or humidity (e.g. no-clean flux) affecting performance for one crystal type versus another?